Essentials: Improving Health With Stronger Brain-Body Connection

Essentials: Improving Health With Stronger Brain-Body Connection

June 05, 2025 40 min
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🤖 AI Summary

Overview

This episode explores interoception—the brain's ability to sense and interpret signals from the body—and its profound impact on health, mood, and performance. Practical tools like breathwork, gut health strategies, and awareness practices are discussed to strengthen the brain-body connection and improve overall well-being.

Notable Quotes

- If you want to be more calm, emphasize exhales. The simplest way to do this is through a physiological sigh: two inhales followed by a long exhale.Andrew Huberman, on using breathwork to regulate stress.

- Your emotions are not just cognitive events; they are shaped by your gut, heart, and breathing, aggregated by the vagus nerve.Andrew Huberman, on the physical roots of emotions.

- Fermented foods far outperform high-fiber diets in reducing inflammation and improving gut microbiome health.Andrew Huberman, on optimizing gut health.

🧠 Brain-Body Communication & Interoception

- Interoception involves sensing mechanical (e.g., heart rate, gut fullness) and chemical (e.g., acidity, nutrient levels) signals from the body.

- The vagus nerve plays a central role in this communication, linking organs like the heart, lungs, and gut to the brain.

- Stress disrupts vagus nerve signaling, impairing digestion and mood regulation.

🌬️ Breathwork for Alertness & Calm

- Breathing mechanics directly influence heart rate and brain states:

- Long inhales increase heart rate and alertness.

- Long exhales slow heart rate and promote calmness.

- The physiological sigh (two inhales, one long exhale) is a quick tool to reduce stress.

- Vigorous inhales followed by short exhales can boost adrenaline and wakefulness, mimicking the effects of caffeine.

🥗 Gut Health & Brain Function

- Gut-brain communication is mediated by neurons that sense stretch and nutrients in the stomach and intestines.

- Tools to improve gut health:

- Replace sugar with omega-3-rich foods to curb cravings.

- Incorporate fermented foods daily to reduce inflammation, enhance immunity, and improve cognitive function.

- Proper gut acidity supports beneficial microbiota, which positively impacts brain and immune health.

🤢 Managing Nausea & Fever

- Nausea is triggered by neurons in the brainstem (area postrema) that detect harmful blood chemistry.

- Ginger (1–3 grams) and cannabinoids (THC or CBD) can effectively reduce nausea.

- Fever is a protective mechanism to cook pathogens but must be managed carefully:

- Cool the palms, soles, and face to safely lower body temperature without triggering further heat production.

❤️ Interoception, Emotions & Social Connection

- Emotions arise from the brain interpreting signals from the heart, gut, and lungs, aggregated by the vagus nerve.

- Practices like heartbeat awareness (e.g., during meditation) enhance interoceptive awareness, improving emotional regulation and intuition.

- Remarkably, humans can subconsciously synchronize heart rates and breathing patterns with others, deepening social connection.

AI-generated content may not be accurate or complete and should not be relied upon as a sole source of truth.

📋 Episode Description

In this Huberman Lab Essentials episode, I discuss interoception, the brain’s ability to sense and interpret signals from the body, which shapes our sense of self and underlies vital functions like focus, sleep, healing and emotions.


I explain how the body communicates different types of information to the brain, influencing processes like digestion, heart rate and immune function.


I also describe practical tools such as breathwork to regulate alertness, strategies to support gut health and reduce sugar cravings, and awareness practices to enhance interoception. By understanding and applying these tools, you can strengthen the brain-body connection to improve mood, overall health and performance.


Read the episode show notes at hubermanlab.com.


Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch or listen to the full-length episode at hubermanlab.com.


Thank you to our sponsors


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Timestamps


00:00:00 Sense of Self, Interoception


00:01:25 Brain & Body Communication, Vagus Nerve, Mechanical & Chemical Information


00:04:43 Lungs & Diaphragm, Tool: Breathwork for Alert or Calm


00:09:47 Sponsors: AG1 & Eight Sleep


00:13:14 Brain & Gut Communication, Tool: Reduce Sugar Cravings


00:18:27 Brain, Gut Chemistry, Inflammation & Gut Microbiome, Tool: Fermented Foods


00:22:20 Sponsor: LMNT


00:23:52 Vomiting, Brain; Tool: Reduce Nausea


00:28:52 Fever, Brain Chemistry, Tool: Cooling Body


00:33:20 Vagus Nerve, Emotions, Mood, Tool: Heart Awareness


00:39:29 Recap & Key Takeaways


Disclaimer & Disclosures

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