Sequoia’s Roelof Botha: Why Venture Capital is Broken & How Great Companies Are Built

Sequoia’s Roelof Botha: Why Venture Capital is Broken & How Great Companies Are Built

October 09, 2025 27 min
🎧 Listen Now

🤖 AI Summary

Overview

This episode features Roelof Botha, a leader at Sequoia Capital, discussing the state of venture capital, Sequoia's unique culture and strategies, the challenges of investing in China, and lessons from legendary founders and mentors. He also delves into the firm's approach to holding winners and the importance of expertise in biotech investing.

Notable Quotes

- Investing in venture is a return-free risk. More money doesn’t create more great ideas or founders.Roelof Botha, on the oversaturation of venture capital.

- Founders don’t take no for an answer. They see the world differently and go fix it.Roelof Botha, on what makes great founders.

- Since launching the Sequoia Capital Fund, we’ve gained $6.7 billion by doing nothing except being patient.Roelof Botha, on the value of holding long-term winners.

🚀 The State of Venture Capital

- Roelof Botha critiques the venture industry for having too much capital chasing too few transformative ideas, calling it return-free risk.

- He highlights the math problem: $200 billion invested annually requires $1 trillion in exits, which is unsustainable given only ~20 companies per decade achieve billion-dollar exits.

- The allure of venture capital, fueled by success stories, attracts more capital, creating a self-perpetuating cycle of overfunding.

🌍 Navigating Global Challenges: China and Beyond

- Sequoia separated from its China business, now called Hongshan, due to increasing geopolitical tensions and regulatory uncertainty.

- Botha notes a 98% drop in new company formations in China since 2018, attributing it to stifling government policies.

- He warns that similar regulatory uncertainty in the U.S., especially around AI, could deter entrepreneurship.

🏛️ Sequoia’s Culture and Decision-Making

- Sequoia emphasizes teamwork and consensus in investment decisions; any partner can veto a deal.

- The firm values insatiable curiosity and a balance of individualism with collaboration in its partners.

- Botha shares how Sequoia’s culture of stewardship ensures generational transitions without financial burdens on incoming leaders.

📈 Holding Winners: The Sequoia Capital Fund

- Sequoia launched the Sequoia Capital Fund to retain shares in companies post-IPO, allowing LPs to benefit from long-term compounding.

- This strategy has added $6.7 billion in gains since its inception, avoiding premature share distributions.

- Botha argues that their deep relationships with founders and early-stage insights make them uniquely positioned to hold public companies.

🧬 Investing in Biotech: Expertise Matters

- While Sequoia has had successes like Natera, Botha admits the firm lacks the expertise for broader biotech investments.

- He cautions against assuming success in one domain translates to others, emphasizing the need for specialized knowledge in biotech and life sciences.

- The firm remains focused on areas where it has a competitive edge, avoiding overreach.

AI-generated content may not be accurate or complete and should not be relied upon as a sole source of truth.

📋 Episode Description

(0:00) Introducing Roelof Botha

(1:08) Sequoia’s Scout program and its best-performing funds ever

(3:38) State of Venture Capital: Why it’s broken, too much capital, not enough great companies

(9:01) Why Sequoia separated from its China business, how they adapt to changing macro landscapes

(13:05) Sequoia’s culture, picking partners, investment decision-making, The Sequoia Capital Fund and holding winners

(20:18) What makes a great founder, what Roelof learned from Doug Leone and Michael Moritz

(26:06) Investing in biotech, importance of expertise in VC

Thanks to our partners for making this happen!

Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana’s global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint

OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/

Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/

IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/

Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/

Circle - The America-based company behind USDC — a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/

BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/

Polymarket - The world’s largest prediction market. https://www.polymarket.com/

Follow Roelof:

https://x.com/roelofbotha

Follow the besties:

https://x.com/chamath

https://x.com/Jason

https://x.com/DavidSacks

https://x.com/friedberg

Follow on X:

https://x.com/theallinpod

Follow on Instagram:

https://www.instagram.com/theallinpod

<