12 Day War, Socialism Wins in NYC, Stocks All-Time High, AI Copyright, Science Corner

12 Day War, Socialism Wins in NYC, Stocks All-Time High, AI Copyright, Science Corner

June 28, 2025 1 hr 47 min
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🤖 AI Summary

Overview

This episode dives into the aftermath of the 12-Day War between Israel and Iran, the rise of socialism in New York City politics, the stock market's record highs, groundbreaking advancements in age reversal science, and the legal battles over AI copyright.

Notable Quotes

- What President Trump has done is almost single-handedly bring back the United States as the global superpower. - Chamath Palihapitiya, on the geopolitical implications of the US-led ceasefire.

- If you can cut your sleep in half, you get an extra 10 years of living. - Chamath Palihapitiya, on the potential of gene editing for reduced sleep needs.

- If we don’t allow a sensible fair use definition for AI, we will lose the AI race to China. - David Sacks, on the importance of balanced copyright policies for AI development.

🌍 The 12-Day War and US-Led Ceasefire

- The US brokered a ceasefire between Israel and Iran after a week of escalating missile strikes and targeted bombings.

- David Sacks praised Trump’s ability to prevent a prolonged war while neutralizing Iran’s nuclear ambitions.

- Chamath Palihapitiya argued this moment reasserts the US as a global superpower, showcasing technological, economic, and military supremacy.

- Concerns remain about the long-term stability in the region, with David Friedberg warning that the conflict may not be over.

🏙️ Socialism’s Rise in NYC Politics

- Democratic Socialist Zohran Mamdani defeated Andrew Cuomo in the Democratic primary for NYC mayor.

- His platform includes free public transit, rent freezes, government-run grocery stores, and a $30 minimum wage.

- David Friedberg linked Mamdani’s rise to economic disillusionment among young, college-educated voters burdened by student debt.

- Chamath Palihapitiya noted that similar policies have failed in cities like London and Chicago, predicting a cyclical return to more conservative governance.

📈 Stock Market at All-Time Highs

- Despite recent geopolitical tensions, the NASDAQ hit record highs, driven by AI innovation, M&A activity, and energy independence.

- Chamath Palihapitiya highlighted the trillions in money market funds poised to flow into equities if rates are cut.

- David Sacks criticized Fed Chair Jerome Powell for being slow to cut rates, arguing inflation is under control.

- The panel debated Powell’s potential replacement, with names like Kevin Warsh and Lael Brainard in contention.

🧬 Science Corner: Age Reversal Breakthroughs

- Chinese researchers used engineered stem cells to reverse aging in monkeys, showing improvements in brain function, muscle growth, and skin rejuvenation.

- David Friedberg explained how the FOXO3 gene triggers cellular rejuvenation, with potential human applications within a decade.

- The team discussed the broader implications of gene editing, including experiments to reduce sleep needs, potentially adding years of productive life.

🤖 AI Copyright Battles

- A federal judge ruled that Anthropic’s use of legally purchased books for AI training was permissible, but pirated content remains a legal gray area.

- David Sacks emphasized the need for a fair use framework to keep US AI competitive against China, which disregards copyright laws.

- Jason Calacanis argued for compensating content creators, suggesting revenue-sharing models akin to music licensing.

- The panel agreed that balancing innovation with intellectual property rights is critical for the future of AI.

AI-generated content may not be accurate or complete and should not be relied upon as a sole source of truth.

📋 Episode Description

(0:00) Bestie intros: The Core Four is back!

(1:38) Launching All-In Tequila!

(7:01) 12 Day War ends in US-led ceasefire: what it means for the future of the region

(29:48) How markets digested the last few weeks in the Middle East, crucial role of energy independence

(39:58) Democratic Socialist Zohran Mamdani upsets Andrew Cuomo in the Democratic Primary for NYC Mayor

(1:06:02) Science Corner: Stem cell-driven aging reversal out of China

(1:18:09) Market at all-time highs after huge turnaround: bull and bear cases; Next Fed chair?

(1:32:49) AI Copyright: Anthropic and Meta receive favorable rulings

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Referenced in the show:

https://abcnews.go.com/Politics/nato-secretary-general-calls-trump-daddy/story?id=123197665

https://x.com/whitehouse/status/1938053287535616085

https://slate.com/news-and-politics/2012/09/benjamin-netanyahu-should-be-careful-about-inserting-himself-too-much-into-the-presidential-race-between-barack-obama-and-mitt-romney.html

https://x.com/DavidSacks/status/1936973199734079907

https://www.washingtonpost.com/national-security/2025/06/23/exclusive-israel-intelligenc