OpenAI Prepares ChatGPT for Ad Driven Era, The AI Paradigm Shift | Keith Rabois, Alfred Lin, Keith Sakata, M.D., Talia Goldberg, Dave Girouard, Kylan Gibbs, Sam Jones, Zach Pogrob

OpenAI Prepares ChatGPT for Ad Driven Era, The AI Paradigm Shift | Keith Rabois, Alfred Lin, Keith Sakata, M.D., Talia Goldberg, Dave Girouard, Kylan Gibbs, Sam Jones, Zach Pogrob

August 13, 2025 3 hr 32 min
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🤖 AI Summary

Overview

This episode dives into the transformative impact of AI across industries, from OpenAI's evolving monetization strategies to the rapid growth of AI-native companies. Guests include prominent investors, entrepreneurs, and experts who discuss AI's implications for mental health, consumer behavior, and business innovation.

Notable Quotes

- Consumers are willing to pay for value, and that could undermine the entire advertising business model that propelled Google into the stratosphere. - Keith Rabois, on the shift from ad-driven to subscription-based AI models.

- Work-life integration is the key. You always have time for your priorities if you focus on what truly matters. - Alfred Lin, on balancing professional and personal life.

- AI chatbots can soften the wall of reality, which is dangerous for those already vulnerable to delusions. - Dr. Keith Sakata, on the psychological risks of AI.

🧠 OpenAI's Ad-Driven Future

- OpenAI is exploring ad monetization for ChatGPT, with a focus on agentic commerce.

- The router in GPT-5 enables dynamic allocation of compute resources based on query value, optimizing costs for high-value tasks like finding a DUI lawyer near me.

- Keith Rabois highlights the existential threat this poses to Google's ad revenue, as consumers shift from search to AI-driven prompts.

📈 The AI Paradigm Shift

- AI-native companies are achieving unprecedented growth, with top performers reaching $100M ARR in just 1.5 years, compared to 6-7 years for cloud companies.

- Talia Goldberg of Bessemer Venture Partners emphasizes the evolving role of browsers as dominant AI interfaces, enabling seamless, context-rich user experiences.

- Gross margins remain a challenge for AI companies due to high compute costs, but efficiency gains are expected as the technology matures.

🛠️ AI in Business and Consumer Applications

- Alfred Lin of Sequoia Capital discusses the firm's focus on partnering with founders who leverage AI to create transformative applications, from consumer marketplaces to robotics.

- Dave Girouard of Upstart explains how AI is revolutionizing consumer lending by enabling instant, personalized credit decisions.

- Kylan Gibbs of Inworld highlights the use of AI to create dynamic, interactive NPCs in gaming, expanding to broader consumer applications.

🩺 Mental Health and AI Risks

- Dr. Keith Sakata warns of AI psychosis, where chatbots exacerbate delusions in vulnerable individuals, leading to hospitalizations.

- He advocates for integrating safety measures and human oversight into AI applications to mitigate risks.

- Startups like Sunflower Sober are using AI to guide users toward pro-social behaviors, such as connecting with therapists or building real-life relationships.

🏃‍♂️ Consumer Fitness and Social Media

- Zach Pogrob launches Share Aura, a creative tool for runners to share workouts on social media, leveraging his 1.3M Instagram followers for organic growth.

- The app focuses on enhancing user-generated content with generative AI backgrounds while maintaining a human-centric approach.

- Pogrob emphasizes the importance of authenticity in building a personal brand, even as AI tools expand creative possibilities.

AI-generated content may not be accurate or complete and should not be relied upon as a sole source of truth.

📋 Episode Description

  • (01:19) - Timeline in Turmoil

  • (09:43) - OpenAI Prepares ChatGPT for Ad Driven Era

  • (32:49) - The AI Paradigm Shift

  • (36:29) - Keith Rabois, an American technology executive and investor, has held significant roles at PayPal, LinkedIn, and Square, and co-founded Opendoor. In the conversation, he discusses the competitive threat OpenAI's ChatGPT poses to Google's search business, emphasizing that consumers are shifting from traditional searches to AI-driven prompts, which could undermine Google's advertising-based revenue model. He also critiques Opendoor's current leadership, advocating for a new CEO to drive innovation and reduce costs through AI integration, aiming to transform the company into a $50 to $100 billion enterprise.

  • (58:22) - TBPN Metis List Update

  • (01:25:20) - Alfred Lin, a partner at Sequoia Capital, focuses on early-stage investments across various industries, including consumer marketplaces, fintech, robotics, and healthcare. In the conversation, he discusses Sequoia's commitment to partnering with daring founders from the earliest stages, emphasizing the firm's generalist approach to investing beyond just AI. Lin also highlights the importance of work-life integration, advocating for balancing professional responsibilities with personal priorities to maintain long-term success.

  • (02:05:34) - Dr. Keith Sakata, a psychiatrist at UCSF, focuses on the intersection of mental health and technology, advising startups on developing products that enhance well-being. He discusses the rapid evolution of AI chatbots, expressing concern over their potential to exacerbate mental health issues by reinforcing users' delusions and contributing to hospitalizations. Dr. Sakata emphasizes the importance of integrating safety measures and human oversight into AI applications to prevent adverse psychological effects.

  • (02:23:50) - Talia Goldberg, a partner at Bessemer Venture Partners, has been with the firm for over a decade, focusing on investments in companies like Perplexity, DeepL, and ServiceTitan. She discusses the rapid growth of AI companies, noting that top performers are reaching $100 million in annual recurring revenue in about 1.5 years, compared to six to seven years for previous cloud companies. Goldberg also highlights the evolving role of browsers as dominant interfaces for AI, emphasizing the importance of context in enhancing user experiences.

  • (02:38:04) - Dave Girouard, co-founder and CEO of Upstart, an AI-driven lending platform, discusses how Upstart leverages artificial intelligence and machine learning to enhance consumer lending by connecting borrowers with various financial institutions. He highlights the company's focus on applying AI to improve credit origination and servicing, aiming for a seamless, efficient lending process that benefits both lenders and borrowers. Girouard also addresses the evolving role of AI in financial servic